2022

2021

 

An infection-induced RhoB-Beclin 1-Hsp90 complex enhances clearance of uropathogenic Escherichia coli.

C. Miao#, M. Yu#, G. Pei, Z. Ma, L. Zhang, J. Yang, J. Lv, Z. Zhang, E. Keller, Z. Yao*, Wang Q*

Nature Communications, 2021, 12:2587. (IF: 18) [link]

 

 

Diagnostic Value of the Fimbriae Distribution Pattern in Localization of Urinary Tract Infection.

Li, X.#, K. Zhou#, J. Wang#, J. Guo, Y. Cao, J. Ren, T. Guan, W. Sheng, M. Zhang, Z. Yao, and Wang Q*

Frontiers in Medicine, 2021. 8: p. 602691. (IF: 5)  [link]

 

 

 

2020

 

Alpha-hemolysin of uropathogenic Escherichia coli induces GM-CSF-mediated acute kidney injury.

C. Wang#, Q. Li#, J. Lv, X. Sun, Y. Cao, K. Yu, C. Miao, Z. S. Zhang, Z. Yao*, Wang Q*

Mucosal Immunology, 2020. 13: 22-33. (IF: 9) [link]

 

 

Cytotoxic necrotizing factor 1 promotes bladder cancer angiogenesis through activating RhoC.

Guo, Y.#, Wang, J.#, Zhou, K., Lv, J., Wang, L., Gao, S., Keller, E., Zhang, Z., Wang Q*, Yao, Z*.

FASEB Journal, 2020. 34: p. 7927-7940. (IF: 6)  [link]

 

 

 

2019

 

Compounds targeting YadC of uropathogenic Escherichia coli and its host receptor annexin A2 decrease bacterial colonization in bladder.

X. Li#, G. Pei#, L. Zhang, Y. Cao, J. Wang, L. Yu, W. Dianjun, S. Gao, Z. S. Zhang, Z. Yao, Wang Q*

EBioMedicine, 2019, 50: 23-33. (IF: 11) [link]

 

 

 

2018

 

Cytotoxic Necrotizing Factor 1 Downregulates CD36 Transcription in Macrophages to Induce Inflammation During Acute Urinary Tract Infections.

Yang H, Li Q, Wang C, Wang J, Lv J, Wang L, Zhang Z, Yao Z*, Wang Q*

Frontiers in Immunology, 2018. 9:1987. (IF: 9)  [link]

 

 

 

2017

 

Cytotoxic necrotizing factor 1 promotes prostate cancer progression through activating the Cdc42-PAK1 axis.

Guo Y#, Zhang Z#, Wei H, Wang J, Lv J, Zhang K, Keller ET, Yao Z*, Wang Q*.

Journal of Pathology, 2017. 243:208-219. (IF: 10)  [link]

 

 

 

2016

 

A High-resolution Typing Assay for Uropathogenic Escherichia coli Based on Fimbrial Diversity.

Ren, Y.#, A. Palusiak#, W. Wang#, Y. Wang, X. Li, H. Wei, Q. Kong, A. Rozalski, Z. Yao, Wang Q*.

Frontiers in Microbiology, 2016. 7: p. 623-632. (IF: 6)   [link]

 

 

 

Before 2016

 

Development of a DNA microarray for detection and serotyping of enterotoxigenic Escherichia coli.

Wang Q, S. Wang, L. Beutin, B. Cao, L. Feng, and L. Wang*

Journal of Clinical Microbiology, 2010. 48(6): p. 2066-74. (IF: 12) [link]

 

 


Development of a multiplex PCR assay for detection and genogrouping of Neisseria meningitidis.

Zhu H.#, Wang Q#, L. Wen, J. Xu, Z. Shao, M. Chen, P.R. Reeves, B. Cao, and L. Wang*

Journal of Clinical Microbiology, 2012. 50(1): p. 46-51. (IF: 12) [link]

 

 


Molecular and genetic analyses of the putative Proteus O antigen gene locus.

Wang Q, A. Torzewska, X. Ruan, X. Wang, A. Rozalski, Z. Shao, X. Guo, H. Zhou, L. Feng, and L. Wang*,

Applied and Environmental Microbiology, 2010. 76(16): p. 5471-8. (IF: 5) [link]

 

 


Structural and genetic characterization of the Escherichia coli O180 O antigen and identification of a UDP-GlcNAc 6-dehydrogenase.

Wang Q#, A.V. Perepelov#, L. Beutin, S.N. Senchenkova, Y. Xu, A.S. Shashkov, P. Ding, Y.A. Knirel, and L. Feng*

Glycobiology, 2012. 22(10): p. 1321-31. (IF: 6) [link]

 


Identification of the two glycosyltransferase genes responsible for the difference between Escherichia coli O107 and O117 O-antigens.

Wang Q#, A.V. Perepelov#, L. Wen, A.S. Shashkov, X. Wang, X. Guo, Y.A. Knirel, and L. Wang*,

Glycobiology, 2012. 22(2): p. 281-7. (IF: 6) [link]

 

 


Characterization of the CDP-D-mannitol biosynthetic pathway in Streptococcus pneumoniae 35A.

Wang Q, Y. Xu, A.V. Perepelov, Y.A. Knirel, P.R. Reeves, A.S. Shashkov, P. Ding, X. Guo, and L. Feng*,

Glycobiology, 2012. 22(12): p. 1760-7. (IF: 6) [link]

 

 


Characterization of the dTDP-D-fucofuranose biosynthetic pathway in Escherichia coli O52.

Wang Q, P. Ding, A.V. Perepelov, Y. Xu, Y. Wang, Y.A. Knirel, L. Wang, and L. Feng*,

Molecular Microbiology, 2008. 70(6): p. 1358-67. (IF: 4) [link]

 

 


Biochemical characterization of the CDP-D-arabinitol biosynthetic pathway in Streptococcus pneumoniae 17F.

Wang Q#, Y. Xu#, A.V. Perepelov, Y.A. Knirel, P.R. Reeves, A.S. Shashkov, X. Guo, P. Ding, and L. Feng*,

Journal of Bacteriology, 2012. 194(8): p. 1868-74. (IF: 3) [link]

 


Characterization of the CDP-2-glycerol biosynthetic pathway in Streptococcus pneumoniae.

Wang Q, Y. Xu, A.V. Perepelov, W. Xiong, D. Wei, A.S. Shashkov, Y.A. Knirel, L. Feng, and L. Wang*,

Journal of Bacteriology, 2010. 192(20): p. 5506-14. (IF: 3) [link]

 

 

Genetic study of capsular switching between Neisseria meningitidis sequence type 7 serogroup A and C strains.

Wang Q#, Z. Shao#, X. Wang, Y. Gao, M. Li, L. Xu, J. Xu*, and L. Wang*,

Infection and Immunity, 2010. 78(9): p. 3883-8. (IF: 4) [link]

 


Development of a serogroup-specific multiplex PCR assay to detect a set of Escherichia coli serogroups based on the identification of their O-antigen gene clusters.

Wang Q, X. Ruan, D. Wei, Z. Hu, L. Wu, T. Yu, L. Feng, and L. Wang*,

Molecular and Cellular Probes, 2010. 24(5): p. 286-90. (IF: 4) [link]

 


Structural and genetic characterization of Shigella boydii type 17 O antigen and confirmation of two new genes involved in the synthesis of glucolactilic acid.

Senchenkova, S.N.#, L. Feng#, Wang Q#, A.V. Perepelov, D. Qin, S.D. Shevelev, Y. Ren, A.S. Shashkov, Y.A. Knirel, and L. Wang*,

Biochemical and Biophysical Research Communicaitons, 2006. 349(1): p. 289-95. (IF: 4) [link]

 


Development of a DNA microarray to identify the Streptococcus pneumoniae serotypes contained in the 23-valent pneumococcal polysaccharide vaccine and closely related serotypes.

Wang Q, M. Wang, F. Kong, G.L. Gilbert, B. Cao, L. Wang*, and L. Feng*,

Journal of Microbiological Methods, 2007. 68(1): p. 128-36. (IF: 3) [link]

 

 

专著:


Wang L, Wang Q, Reeves P. 2010. The variation of O antigens in Gram-negative bacteria. In X. Wang, P. J. Quinn (eds.), Endotoxins: Structure, Function and Recognition, Springer, New York, USA.  

 

 

专利:


一种基于菌毛多样性的尿路感染大肠杆菌的分型方法。王荃。专利号:ZL201510022361.0。2017年2月22日授权。已转化。
靶向菌毛黏附素YadC的宿主受体ANXA2用于改善急性下尿路感染。王荃,李晓,裴庚。ZL201910957083.6。2022年5月24日授权。
一种基于菌毛抗原基因分布对尿路感染部位进行定位判断的方法。王荃,李晓,周开臣。申请号:202010106384.0。
对大肠杆菌O134型的O-抗原特异的核苷酸。王磊,王荃,冯露。 专利号:ZL200410094100.1。2007年5月16日授权。
变形杆菌多种血清型菌株特异性引物及多重PCR检测方法。王磊,王荃,彭志勇,冯露。专利号:201310115652.5。2014年11月26日授权。
一种在革兰氏阳性菌中合成的CDP-2-甘油及其制备方法。王磊,徐艳丽,王荃,冯露。专利号 201010141807.9。2014年2月5日授权。

 

 
 

RhoB Affects Colitis through Modulating Cell Signaling and Intestinal Microbiome

 

J. Yang, G. Pei, X. Sun, Y. Xiao, C. Miao, L. Zhou, B. Wang, L. Yang, M. Yu, Z. Zhang, E.  Keller, Z. Yao, Wang Q*

 

Microbiome, 2022, 10:149. (IF: 17)  [link]

 

 

Enterobacter ludwigii protects DSS-induced colitis through choline-mediated immune tolerance

 

Q. Li, X. Sun, K. Yu, J. Lv, C. Miao, J. Yang, S. Wang, Z. Fu, Y. Sun, H. Zhang, Z. Zhang, E. Keller, Z. Yao*, Wang Q*

 

Cell Reports, 2022, 40:111308. (IF: 10)  [link]

 

Interactions of Bacterial Toxin CNF1 and Host JAK1/2 Driven by Liquid-Liquid Phase Separation Enhance Macrophage Polarization

 

Sun, X#, J. Yang#, X. Deng#, Y. Wei, C. Wang, Y. Guo, H. Yang, L. Yang, C. Miao, J. Lv, Y. Xiao, H. Zhang, Z. Yao*, and Wang Q*

 

mBio, 2022, 13(4): e0114722. (IF: 8)  [link]

论文与专利

HSPA8 regulates anti-bacterial autophagy through
liquid-liquid phase separation

 

Chunhui Miao, Yajie Zhang, Mingyu Yu, Yuting Wei, Cheng Dong, Geng Pei, Yawen Xiao, Jianming Yang, Z. Yao & Wang Q*

 

Autophagy , 2023, 10.1080. (IF: 13)  [link]

 

 

2023

 

 

Bacterial indole-3-lactic acid affects epithelium–macrophagecrosstalk to regulate intestinal homeostasis
 

Kaiyuan Yu , Qianqian Li , Xuan Sun , Xianping Peng , Qiang Tang , Hongyu Chu , Lu Zhou , Bangmao Wang , Zhemin Zhou , Xueqin Deng , Jianming Yang , Junqiang Lv , Ran Liu , Chunhui Miao , Wei Zhao , Zhi Yao1, and Quan Wang,1

PNAS , 2023,10.1073.(IF: 11) [link]